This clinical case report illustrates an example of chronic myeloid leukaemia (CML). The XN-Series analyser identified abnormal scattergrams and multiple flags such as ‘Blasts/Abn Lympho?’, ‘IG Present’ or ‘Basophilia’. These findings led to a blood smear and digital imaging identified massive numbers of neutrophils and IG.
The lab card illustrates the value of the RET application and points to the advanced clinical parameter RET-He (reticulocyte haemoglobin equivalent) and IRF (immature reticulocyte fraction). Front side addresses the core messages for lab and clinical benefits, flip side contains technical information.
This white paper intents to give an overview of the most common types of anaemia with a focus on how haematological parameters such as RET-He and other advanced RBC parameters could help to distinguish different causes of anaemia. The white paper also summarises current guidelines and publications on advanced RBC parameters.
Haemostasis is a complex process that helps to keep the blood in a fluid state and prevent blood loss at the site of injury. While the intact endothelium of blood vessels has an anti-thrombogenic function that prevents blood coagulation, in the case of vessel wall damage, the exposed sub-endothelial components initiate the formation of a clot that will stop blood loss.
The clinical information card describes the clinical challenges during haematopoietic stem cell transplantation (HSCT) treatment. The case of an oncologic patient is described and the benefits of our analysers for monitoring of infections, thrombocytopenia and engraftment are emphasised.
The detection of blast cells in the peripheral blood is considered extremely important, and great responsibility is placed on the investigating laboratory. As well as informa¬tion on the physiology, this SEED article describes the possible causes of the release of blast cells into the blood, the char¬acteristics by which they can be identified and how further diagnosis is carried out.
This SEED article is meant to explain the findings focused on cell count and differentiation for pleural, ascitic, cerebrospinal and synovial fluid as well as for CAPD. Traditionally, body fluid counts are performed by manual counting under a microscope using a haemocytometer, but laboratories now have the option of automating their manual processes using automated haematology or urinalysis analysers. This SEED summarises the advantages and disadvantages of haemocytometry and Sysmex analysers and explains briefly the XN-BF mode.